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Recurrent Pregnancy Loss
Recurrent pregnancy loss (RPL) is defined as two or more consecutive pregnancy losses before the 20th week of gestation. It affects approximately 1-2% of couples trying to conceive and can be a distressing condition requiring medical evaluation and intervention.
What is Recurrent Pregnancy Loss?
Recurrent pregnancy loss (RPL) is defined as two or more consecutive pregnancy losses before the 20th week of gestation. It affects approximately 1-2% of couples trying to conceive and can be a distressing condition requiring medical evaluation and intervention.
Recurrent pregnancy loss (RPL) is defined as two or more consecutive pregnancy losses before the 20th week of gestation. It affects approximately 1-2% of couples trying to conceive and can be a distressing condition requiring medical evaluation and intervention.
Genetic Factors
Chromosomal abnormalities in the embryo, often due to parental genetic translocations.
Aneuploidy, an abnormal number of chromosomes in the embryo.
Anatomical Causes
Uterine septum, fibroids, or adhesions that interfere with implantation.
Cervical insufficiency leading to second-trimester losses.
Hormonal and Metabolic Disorders
Thyroid dysfunction, including hypothyroidism or hyperthyroidism.
Uncontrolled diabetes or polycystic ovary syndrome (PCOS).
Luteal phase deficiency, leading to inadequate progesterone levels.
Autoimmune and Blood Clotting Disorders
Antiphospholipid syndrome (APS), which causes blood clots that impair pregnancy.
Thrombophilia, a predisposition to abnormal blood clotting.
Infections and Environmental Factors
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